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Reese Witherspoon and Jim Toth are co-executive producers on the 2021 edition of Stand Up To Cancer (SU2C), working alongside the renowned live-event producing team Done + Dusted and Stand Up To Cancer’s production team. Anthony Anderson, Ken Jeong & Tran Ho, and Sofia Vergara will serve as cohosts with performances by Common and Brittany Howard and more. 

“Cancer is the second leading cause of death in the U.S. and the leading cause in Canada,” Reese Witherspoon said in a statement. “Unfortunately, too many of us have a personal experience with this disease. I’m proud to highlight the amazing doctors and scientists of Stand Up To Cancer who work tirelessly on important cancer research, innovative treatments and much needed patient care.”

“Having lost my father to this disease, it is a privilege for us to continue to support the important work of Stand Up To Cancer as co-producers of the telecast,” Jim Toth added. 

Since its inception, SU2C has raised more than $603 million to bring together more than 1,950 scientists from more than 210 institutions to collaborate towards ending cancer’s reign as a leading cause of death worldwide. SU2C’s research has contributed to nine FDA approvals for new cancer therapies and 258 clinical trials treating more than 19,000 patients. Acknowledging that improving cancer care is a critical need in medically underserved communities, SU2C began developing its Health Equity Initiative in 2017. The initiative's goal is to increase diverse enrollment in cancer clinical trials, fund innovative research that addresses cancer inequities, and raise awareness of the importance of cancer screenings.


“I’m proud to highlight the amazing doctors and scientists of Stand Up To Cancer who work tirelessly on important cancer research, innovative treatments and much needed patient care.”
— Reese Witherspoon

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