Guests: Fareed Zakaria, journalist; Richard Engel, news correspondent; Rep. Barney Frank (D-MA); David Kessler, former FDA chief

On The Supreme Court

We will die, many of us, being haunted by Antonin Scalia's bigotry being practiced on the U.S. Supreme Court.  Rep. Barney Frank

The Supreme Court is right now very substantially to the right of the country because of 30 years of essentially Republican domination of the executive branch.  Fareed Zakaria

Generally, what the courts can do is to stop you from doing bad things. They can't make you do good things.  Rep. Barney Frank

On Lawyers

I'm not a lawyer, but I know this much: the law is what they make up as they go along.  Bill Maher

On Political Parties

Arlen Specter switching sides was like Dylan going electric.  Bill Maher

I want to control the major Democratic Party. If people think we're too liberal, let them start the second party.  Rep. Barney Frank

The 'Party of Lincoln' is becoming the 'Party of Shrinkin' at this point.  Bill Maher

We do need two parties. I think five or ten would be better, but we need at least two.  Bill Maher

On the Middle East

One of the things America could learn from Israel is how not to totally panic in the face of what you think is a threat.  Rep. Barney Frank

If there are members of the Taliban that want to negotiate and don't want to fight anymore, that should be absolutely encouraged.  Dr. Howard Dean

[Teddy] Roosevelt also showed that you could be pro-nature and still kill a lot of animals.  Randy Cohen

How come we can't be friends with Cuba, but we're friends with a country [Saudi Arabia] that marries an eight-year-old girl?  Bill Maher