Wilson made his acting debut in the critically acclaimed independent film, ‘Bottle Rocket.' The film was the first written and directed by Wes Anderson and co-written by his brother, Owen, who also co-starred. Following ‘Bottle Rocket,' Wilson went onto appear in various cameo and supporting roles before winning lead roles in Bruce McCulloch's ‘Dog Park' and in ‘Home Fries' opposite Drew Barrymore. Luke re-teamed with Owen Wilson and Wes Anderson for ‘Rushmore' and ‘The Royal Tenenbaums.' In 2003, Wilson co-starred with Vince Vaughn and Will Ferrell in ‘Old School'. Other recent film credits include Rob Reiner's romantic comedy, ‘Alex & Emma' and ‘Masked & Anonymous' opposite Bob Dylan, Penelope Cruz, and Jessica Lange. Wilson also appeared with Martin Lawrence in the hit comedy, ‘Blue Streak,' and opposite Heather Graham in ‘Committed,' which was nominated for a Grand Jury Prize at the 2000 Sundance Film Festival. He appeared in the hit, ‘Charlie's Angels,' and starred opposite Reese Witherspoon in ‘Legally Blonde,' which was nominated for a Golden Globe Award for Best Motion Picture - Musical or Comedy. In addition, Wilson reprised his roles for both sequels. Wilson made his directorial and writing debut in the romantic comedy ‘The Wendell Baker Story,' in which he stars. His oldest brother Andrew Wilson co-directed the film with Luke. Wilson most recently starred in ‘The Family Stone' with Sarah Jessica Parker. He next appears in Wil Shriner's film adaptation of the Carl Hiaasen Newbery-honored novel, ‘Hoot.'